DLG2 and GRID1 |
discs large MAGUK scaffold protein 2 |
glutamate ionotropic receptor delta type subunit 1 |
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- RAF/MAP kinase cascade
- Neurexins and neuroligins
- Neurexins and neuroligins
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
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DLG2 and GRIN1 |
discs large MAGUK scaffold protein 2 |
glutamate ionotropic receptor NMDA type subunit 1 |
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- RAF/MAP kinase cascade
- Neurexins and neuroligins
- Neurexins and neuroligins
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
|
- EPHB-mediated forward signaling
- EPHB-mediated forward signaling
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- RAF/MAP kinase cascade
- Neurexins and neuroligins
- Synaptic adhesion-like molecules
- Assembly and cell surface presentation of NMDA receptors
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
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- Glutamic Acid
- Atomoxetine
- Pentobarbital
- Secobarbital
- Pethidine
- Acamprosate
- Gabapentin
- Memantine
- Orphenadrine
- Phenobarbital
- Prasterone
- Dcka, 5,7-Dichlorokynurenic Acid
- D-Serine
- Cycloleucine
- Milnacipran
- CNS-5161
- Acetylcysteine
- Ketobemidone
- Gavestinel
- Agmatine
- Ifenprodil
- Magnesium acetate tetrahydrate
- Magnesium carbonate
- Fluciclovine (18F)
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DLG2 and GRIN2A |
discs large MAGUK scaffold protein 2 |
glutamate ionotropic receptor NMDA type subunit 2A |
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- RAF/MAP kinase cascade
- Neurexins and neuroligins
- Neurexins and neuroligins
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
|
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Neurexins and neuroligins
- Synaptic adhesion-like molecules
- MECP2 regulates neuronal receptors and channels
- Assembly and cell surface presentation of NMDA receptors
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
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|
- Glutamic Acid
- Glycine
- Atomoxetine
- Pentobarbital
- Secobarbital
- Pethidine
- Acamprosate
- Felbamate
- Gabapentin
- Memantine
- Halothane
- Phenobarbital
- Tenocyclidine
- Prasterone
- Milnacipran
- Acetylcysteine
- Ketobemidone
- Gavestinel
- Magnesium acetate tetrahydrate
- Magnesium carbonate
- Fluciclovine (18F)
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DLG2 and GRIN2B |
discs large MAGUK scaffold protein 2 |
glutamate ionotropic receptor NMDA type subunit 2B |
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- RAF/MAP kinase cascade
- Neurexins and neuroligins
- Neurexins and neuroligins
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
|
- EPHB-mediated forward signaling
- EPHB-mediated forward signaling
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- RAF/MAP kinase cascade
- Neurexins and neuroligins
- Synaptic adhesion-like molecules
- MECP2 regulates neuronal receptors and channels
- Activated NTRK2 signals through FYN
- Assembly and cell surface presentation of NMDA receptors
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
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|
- Glutamic Acid
- Atomoxetine
- Pentobarbital
- Secobarbital
- Pethidine
- Haloperidol
- Acamprosate
- Felbamate
- Gabapentin
- Memantine
- Phenobarbital
- Tenocyclidine
- Prasterone
- Taurine
- Milnacipran
- Acetylcysteine
- Ketobemidone
- Gavestinel
- Ifenprodil
- Magnesium acetate tetrahydrate
- Magnesium carbonate
- Fluciclovine (18F)
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DLG2 and GRIN2D |
discs large MAGUK scaffold protein 2 |
glutamate ionotropic receptor NMDA type subunit 2D |
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- RAF/MAP kinase cascade
- Neurexins and neuroligins
- Neurexins and neuroligins
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
|
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- RAF/MAP kinase cascade
- Neurexins and neuroligins
- Synaptic adhesion-like molecules
- Assembly and cell surface presentation of NMDA receptors
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
|
|
- Glutamic Acid
- Atomoxetine
- Pentobarbital
- Secobarbital
- Pethidine
- Acamprosate
- Gabapentin
- Orphenadrine
- Phenobarbital
- Tenocyclidine
- Prasterone
- Milnacipran
- Acetylcysteine
- Ketobemidone
- Gavestinel
- Magnesium acetate tetrahydrate
- Magnesium carbonate
- Fluciclovine (18F)
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DLG2 and NOS1 |
discs large MAGUK scaffold protein 2 |
nitric oxide synthase 1 |
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- RAF/MAP kinase cascade
- Neurexins and neuroligins
- Neurexins and neuroligins
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
|
- ROS and RNS production in phagocytes
- Nitric oxide stimulates guanylate cyclase
- Ion homeostasis
|
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- L-Citrulline
- L-N(Omega)-Nitroarginine-2,4-L-Diaminobutyric Amide
- Formic Acid
- 3-Bromo-7-Nitroindazole
- N-{(4s)-4-Amino-5-[(2-Aminoethyl)Amino]Pentyl}-N'-Nitroguanidine
- N-(3-(Aminomethyl)Benzyl)Acetamidine
- L-N(Omega)-Nitroarginine-(4r)-Amino-L-Proline Amide
- N-Isopropyl-N'-Hydroxyguanidine
- N-Omega-Propyl-L-Arginine
- N-Butyl-N'-Hydroxyguanidine
- S-Ethyl-N-[4-(Trifluoromethyl)Phenyl]Isothiourea
- N-Omega-Hydroxy-L-Arginine
- Flavin adenine dinucleotide
- Riboflavin Monophosphate
- N-(4-(2-((3-Chlorophenylmethyl)Amino)Ethyl)Phenyl)-2-Thiophecarboxamidine
- 2'-Monophosphoadenosine 5'-Diphosphoribose
- S-Ethyl-N-Phenyl-Isothiourea
- N5-(1-Imino-3-Butenyl)-L-Ornithine
- 5-N-Allyl-Arginine
- Nitroarginine
- NXN-188
- N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE
- N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine
- Methylene blue
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DLG2 and LIN7A |
discs large MAGUK scaffold protein 2 |
lin-7 homolog A, crumbs cell polarity complex component |
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- RAF/MAP kinase cascade
- Neurexins and neuroligins
- Neurexins and neuroligins
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
|
- Dopamine Neurotransmitter Release Cycle
- Neurexins and neuroligins
- Assembly and cell surface presentation of NMDA receptors
|
|
|
|
|
DLG2 and SEMA4C |
discs large MAGUK scaffold protein 2 |
semaphorin 4C |
- Unblocking of NMDA receptors, glutamate binding and activation
- Unblocking of NMDA receptors, glutamate binding and activation
- Ras activation upon Ca2+ influx through NMDA receptor
- RAF/MAP kinase cascade
- Neurexins and neuroligins
- Neurexins and neuroligins
- Assembly and cell surface presentation of NMDA receptors
- Negative regulation of NMDA receptor-mediated neuronal transmission
- Long-term potentiation
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DMD and CADPS |
dystrophin |
calcium dependent secretion activator |
- Non-integrin membrane-ECM interactions
- Striated Muscle Contraction
|
|
|
- Calcium Citrate
- Calcium Phosphate
|
- Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
- Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
- Dilated cardiomyopathy (DCM)
|
|
DMD and SGCZ |
dystrophin |
sarcoglycan zeta |
- Non-integrin membrane-ECM interactions
- Striated Muscle Contraction
|
|
|
|
- Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
- Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
- Dilated cardiomyopathy (DCM)
|
|
DMD and KRT8 |
dystrophin |
keratin 8 |
- Non-integrin membrane-ECM interactions
- Striated Muscle Contraction
|
- Keratinization
- Formation of the cornified envelope
|
|
|
- Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
- Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
- Dilated cardiomyopathy (DCM)
|
|
DMD and DGKZ |
dystrophin |
diacylglycerol kinase zeta |
- Non-integrin membrane-ECM interactions
- Striated Muscle Contraction
|
- Effects of PIP2 hydrolysis
|
|
|
- Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
- Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
- Dilated cardiomyopathy (DCM)
|
|
DMD and CTNNAL1 |
dystrophin |
catenin alpha like 1 |
- Non-integrin membrane-ECM interactions
- Striated Muscle Contraction
|
|
|
|
- Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
- Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
- Dilated cardiomyopathy (DCM)
|
|
DMD and PGM5 |
dystrophin |
phosphoglucomutase 5 |
- Non-integrin membrane-ECM interactions
- Striated Muscle Contraction
|
|
|
|
- Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
- Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
- Dilated cardiomyopathy (DCM)
|
|
DMD and TRAF3IP1 |
dystrophin |
TRAF3 interacting protein 1 |
- Non-integrin membrane-ECM interactions
- Striated Muscle Contraction
|
- Intraflagellar transport
- Intraflagellar transport
|
|
|
- Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
- Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
- Dilated cardiomyopathy (DCM)
|
|
DMD and DISC1 |
dystrophin |
DISC1 scaffold protein |
- Non-integrin membrane-ECM interactions
- Striated Muscle Contraction
|
|
|
|
- Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
- Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
- Dilated cardiomyopathy (DCM)
|
|
DMD and KRT19 |
dystrophin |
keratin 19 |
- Non-integrin membrane-ECM interactions
- Striated Muscle Contraction
|
- Keratinization
- Formation of the cornified envelope
|
|
|
- Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
- Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
- Dilated cardiomyopathy (DCM)
|
|
DMD and DTNA |
dystrophin |
dystrobrevin alpha |
- Non-integrin membrane-ECM interactions
- Striated Muscle Contraction
|
|
|
|
- Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
- Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
- Dilated cardiomyopathy (DCM)
|
|
DMD and DTNB |
dystrophin |
dystrobrevin beta |
- Non-integrin membrane-ECM interactions
- Striated Muscle Contraction
|
|
|
|
- Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
- Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
- Dilated cardiomyopathy (DCM)
|
|
DMD and KCNJ12 |
dystrophin |
potassium inwardly rectifying channel subfamily J member 12 |
- Non-integrin membrane-ECM interactions
- Striated Muscle Contraction
|
- Activation of G protein gated Potassium channels
- Classical Kir channels
- Phase 4 - resting membrane potential
- Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
|
|
|
- Glycerol kinase deficiency (GKD), including: Hyperglycerolemia; Chromosome Xp21 deletion syndrome; Adrenal hypoplasia, congenital (AHC); Duchenne muscular dystrophy (DMD)
- Dystrophinopathies, including: Duchenne muscular dystrophy (DMD); Becker muscular dystrophy (BMD); X-linked dilated cardiomyopathy (XLCM)
- Dilated cardiomyopathy (DCM)
|
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