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MELK

Description maternal embryonic leucine zipper kinase
Image
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Plasma Membrane
  • Cell Cortex
  • Membrane
Molecular Function
  • Protein Serine/threonine Kinase Activity
  • Non-membrane Spanning Protein Tyrosine Kinase Activity
  • Calcium Ion Binding
  • Protein Binding
  • ATP Binding
  • Lipid Binding
Biological Process
  • G2/M Transition Of Mitotic Cell Cycle
  • Protein Phosphorylation
  • Apoptotic Process
  • Cell Proliferation
  • Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress
  • Peptidyl-tyrosine Phosphorylation
  • Hemopoiesis
  • Intracellular Signal Transduction
  • Positive Regulation Of Apoptotic Process
  • Protein Autophosphorylation
  • Neural Precursor Cell Proliferation
Pathways
Drugs
Diseases
GWAS
Interacting Genes 10 interacting genes: CDC25B CDC5L EIF2S1 H1-5 LMNB1 MAPT MBP PPP1R8 SF3B1 ZNF622
Entrez ID 9833
HPRD ID 06119
Ensembl ID ENSG00000165304
Uniprot IDs B7Z1G6 Q14680
PDB IDs 4BKY 4BKZ 4BL1 4D2P 4D2T 4D2V 4D2W 4IXP 4UMP 4UMQ 4UMR 4UMT 4UMU 5IH8 5IH9 5IHA 5IHC 5K00 5M5A 5MAF 5MAG 5MAH 5MAI 5TVT 5TWL 5TWU 5TWY 5TWZ 5TX3 6GVX
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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