ISG15

Description		ISG15 ubiquitin like modifier
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GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Integrin Binding Protein Binding Protein Tag Ubiquitin Protein Ligase Binding
	Biological Process	Integrin-mediated Signaling Pathway Viral Process Protein Ubiquitination Modification-dependent Protein Catabolic Process Translesion Synthesis Positive Regulation Of Bone Mineralization Negative Regulation Of Protein Ubiquitination ISG15-protein Conjugation Negative Regulation Of Type I Interferon Production Regulation Of Interferon-gamma Production Response To Type I Interferon Defense Response To Bacterium Negative Regulation Of Viral Genome Replication Positive Regulation Of Erythrocyte Differentiation Defense Response To Virus Type I Interferon Signaling Pathway Interleukin-10 Secretion Interferon-gamma Secretion
Pathways		ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways DDX58/IFIH1-mediated induction of interferon-alpha/beta Termination of translesion DNA synthesis Interferon alpha/beta signaling Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488)
Interacting Genes		6 interacting genes: HDAC6 HIF1A SQSTM1 UBA7 USP18 USP21
Entrez ID		9636
HPRD ID		00958
Ensembl ID		ENSG00000187608
Uniprot IDs		P05161
PDB IDs		1Z2M 2HJ8 3PHX 3PSE 3R66 3RT3 3SDL 5TL6 5W8T 5W8U 6BI8 6FFA
Enriched GO Terms of Interacting Partners?
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