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IL27RA

Description interleukin 27 receptor subunit alpha
Image No pdb structure
GO Annotations Cellular Component
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • External Side Of Plasma Membrane
  • Receptor Complex
Molecular Function
  • Transmembrane Signaling Receptor Activity
  • Cytokine Receptor Activity
  • Cytokine Binding
  • Interleukin-27 Receptor Activity
Biological Process
  • Positive Regulation Of T-helper 1 Type Immune Response
  • Negative Regulation Of Type 2 Immune Response
  • Immune Response
  • Cell Surface Receptor Signaling Pathway
  • Positive Regulation Of Interferon-gamma Production
  • Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
  • Regulation Of Isotype Switching To IgG Isotypes
  • Defense Response To Gram-positive Bacterium
  • Interleukin-27-mediated Signaling Pathway
  • Interleukin-35-mediated Signaling Pathway
  • Negative Regulation Of Interleukin-6 Secretion
  • Negative Regulation Of Tumor Necrosis Factor Secretion
  • Negative Regulation Of Interleukin-17 Secretion
  • Negative Regulation Of T-helper 17 Type Immune Response
  • Negative Regulation Of T Cell Extravasation
Pathways
  • Interleukin-35 Signalling
  • Interleukin-27 signaling
  • Interleukin-27 signaling
Drugs
Diseases
GWAS
  • Blood protein levels ( 30072576 29875488)
  • Immune response to measles-mumps-rubella vaccine ( 24811271)
Interacting Genes 5 interacting genes: EBI3 GDF15 IL27 MAPK8 STAT1
Entrez ID 9466
HPRD ID 09247
Ensembl ID ENSG00000104998
Uniprot IDs Q6UWB1
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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