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KRIT1

Description KRIT1 ankyrin repeat containing
Image
GO Annotations Cellular Component
  • Extracellular Space
  • Cell
  • Cytoplasm
  • Cytoskeleton
  • Plasma Membrane
  • Cell-cell Junction
Molecular Function
  • Protein Binding
  • Phosphatidylinositol-4,5-bisphosphate Binding
  • Microtubule Binding
  • GTPase Regulator Activity
Biological Process
  • Angiogenesis
  • Negative Regulation Of Endothelial Cell Proliferation
  • Small GTPase Mediated Signal Transduction
  • Negative Regulation Of Endothelial Cell Migration
  • Negative Regulation Of Angiogenesis
  • Cell Redox Homeostasis
  • Regulation Of Catalytic Activity
  • Regulation Of Establishment Of Cell Polarity
  • Negative Regulation Of Endothelial Cell Apoptotic Process
Pathways
Drugs
Diseases
  • Cerebral cavernous malformation
GWAS
  • Coffee consumption ( 31046077)
  • Hippocampal volume in Alzheimer's disease dementia ( 29274321)
Interacting Genes 6 interacting genes: FAS ITGB1BP1 PLCB3 RAP1A RGS4 TRPV4
Entrez ID 889
HPRD ID 05020
Ensembl ID ENSG00000001631
Uniprot IDs A4D1F7 O00522
PDB IDs 3U7D 4DX8 4DXA 4HDO 4HDQ 4JIF 4TKN 5D68
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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