HESX1

Description		HESX homeobox 1
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Protein C-terminus Binding Protein N-terminus Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Brain Development Pituitary Gland Development Otic Vesicle Formation Nose Development Forebrain Morphogenesis
Pathways
Drugs
Diseases		Septo-optic dysplasia Pituitary Dwarfism (PD); Isolated growth hormone deficiency (IGHD); Short Stature and Pituitary Defects (SSPD); Insulin-like growth factor 1 deficiency (IGFD)
GWAS		Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256)
Interacting Genes		7 interacting genes: KDM1A NCOR1 NPAS2 PRMT6 PROP1 STAT3 TLE1
Entrez ID		8820
HPRD ID		03482
Ensembl ID		ENSG00000163666
Uniprot IDs		A1LQR0 Q9UBX0
PDB IDs		2K40
Enriched GO Terms of Interacting Partners?
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