TTBK1

Description		tau tubulin kinase 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Neuronal Cell Body Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity ATP Binding Tau Protein Binding Tau-protein Kinase Activity
	Biological Process	Protein Phosphorylation Learning Or Memory Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Substantia Nigra Development Negative Regulation Of Protein Binding Positive Regulation Of Protein Polymerization Positive Regulation Of Astrocyte Activation Positive Regulation Of Microglial Cell Activation Positive Regulation Of Cyclin-dependent Protein Kinase Activity Positive Regulation Of Cysteine-type Endopeptidase Activity
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Drugs
Diseases
GWAS		Adult hearing difficulty ( 31564434) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Diastolic blood pressure ( 29403010) Estimated glomerular filtration rate in non-diabetics ( 31451708) General cognitive ability ( 29844566) Mean arterial pressure ( 29403010) Pulse pressure ( 28739976) Systolic blood pressure ( 26390057 29403010 28739976)
Interacting Genes		5 interacting genes: CDK5R1 CSN1S1 MAP2 MAPT TUBB
Entrez ID		84630
HPRD ID		11653
Ensembl ID		ENSG00000146216
Uniprot IDs		Q5TCY1
PDB IDs		4BTJ 4BTK 4BTM 4NFM 4NFN
Enriched GO Terms of Interacting Partners?
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