TEAD2

Description		TEA domain transcription factor 2
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytosol Intracellular Membrane-bounded Organelle TEAD-2-YAP Complex
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Transcription Factor Binding Transcription Coactivator Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Protein Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity Disordered Domain Specific Binding
	Biological Process	Vasculogenesis Neural Tube Closure Embryonic Heart Tube Morphogenesis Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Notochord Development Hippo Signaling Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Paraxial Mesoderm Development Lateral Mesoderm Development Embryonic Organ Development Negative Regulation Of Cell Death Protein-containing Complex Assembly Cellular Response To Retinoic Acid Regulation Of Stem Cell Differentiation
Pathways		YAP1- and WWTR1 (TAZ)-stimulated gene expression RUNX3 regulates YAP1-mediated transcription
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Diseases
GWAS
Interacting Genes		37 interacting genes: AKT1 ARNT AURKA BCL2L15 BECN1 CCND2 CDK4 CDK6 CDKN2A CDKN2B DACH1 EPHA2 FGFR4 FZR1 GLIS1 GLIS2 HGF HIF1A LATS2 MAP2K3 MAP2K5 MAP3K5 MYC NCOA1 NEDD4 NFIC NSD3 RAF1 RASSF1 SAA2 SOX3 STK11 TERT TP53 USF2 VGLL1 YAP1
Entrez ID		8463
HPRD ID		03432
Ensembl ID		ENSG00000074219
Uniprot IDs		A0A024QZE2 Q15562
PDB IDs		3L15 5DQ8 5DQE 5EMV 5HGU 6E5G
Enriched GO Terms of Interacting Partners?
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