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RECK

Description reversion inducing cysteine rich protein with kazal motifs
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
  • Plasma Membrane
  • Membrane
  • Anchored Component Of Membrane
  • Wnt Signalosome
Molecular Function
  • Endopeptidase Inhibitor Activity
  • Serine-type Endopeptidase Inhibitor Activity
  • Protein Binding
  • Metalloendopeptidase Inhibitor Activity
  • Wnt-protein Binding
  • Coreceptor Activity Involved In Canonical Wnt Signaling Pathway
Biological Process
  • Vasculature Development
  • Blood Vessel Maturation
  • Sprouting Angiogenesis
  • Embryo Implantation
  • Negative Regulation Of Endopeptidase Activity
  • Extracellular Matrix Organization
  • Negative Regulation Of Cell Migration
  • Embryonic Forelimb Morphogenesis
  • Regulation Of Angiogenesis
  • Canonical Wnt Signaling Pathway
  • Regulation Of Establishment Of Blood-brain Barrier
  • Positive Regulation Of Canonical Wnt Signaling Pathway
  • Negative Regulation Of Metalloendopeptidase Activity
Pathways
  • Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS
  • Bipolar disorder (inflammation and infection response interaction) ( 25781172)
  • IgG glycosylation ( 23382691)
Interacting Genes 15 interacting genes: CEP44 CTH KEAP1 KRT40 MEOX2 MMP9 MTNR1B NOTCH2NLA REL SIGMAR1 TCF4 TEKT4 TRIM39 TRIM69 USHBP1
Entrez ID 8434
HPRD ID 05567
Ensembl ID ENSG00000122707
Uniprot IDs A8K9D8 O95980 Q6P9E2
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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