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CAPZA2

Description capping actin protein of muscle Z-line subunit alpha 2
Image No pdb structure
GO Annotations Cellular Component
  • Extracellular Region
  • Cytosol
  • Brush Border
  • F-actin Capping Protein Complex
  • Actin Cytoskeleton
  • Membrane
  • Actin Cortical Patch
  • Extracellular Exosome
Molecular Function
  • Protein Binding
  • Actin Filament Binding
Biological Process
  • ER To Golgi Vesicle-mediated Transport
  • Blood Coagulation
  • Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
  • Actin Cytoskeleton Organization
  • Innate Immune Response
  • Barbed-end Actin Filament Capping
  • Protein-containing Complex Assembly
Pathways
  • MHC class II antigen presentation
  • HSP90 chaperone cycle for steroid hormone receptors (SHR)
  • COPI-mediated anterograde transport
  • COPI-independent Golgi-to-ER retrograde traffic
  • Advanced glycosylation endproduct receptor signaling
  • Factors involved in megakaryocyte development and platelet production
  • Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
  • Mean platelet volume ( 27863252)
  • Platelet count ( 27863252)
  • Platelet distribution width ( 27863252)
  • Plateletcrit ( 27863252)
  • Pulse pressure ( 27841878)
  • Waist-to-hip ratio adjusted for BMI ( 26426971)
  • Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes 3 interacting genes: CAPZA3 HSPB2 RBBP6
Entrez ID 830
HPRD ID 11871
Ensembl ID ENSG00000198898
Uniprot IDs A4D0V4 P47755
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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