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CUL5

Description cullin 5
Image
GO Annotations Cellular Component
  • Cytosol
  • SCF Ubiquitin Ligase Complex
  • Cullin-RING Ubiquitin Ligase Complex
  • Cul5-RING Ubiquitin Ligase Complex
  • Site Of DNA Damage
Molecular Function
  • Ubiquitin-protein Transferase Activity
  • Calcium Channel Activity
  • Protein Binding
  • Ubiquitin Protein Ligase Binding
  • Signaling Receptor Activity
Biological Process
  • G1/S Transition Of Mitotic Cell Cycle
  • Ubiquitin-dependent Protein Catabolic Process
  • Viral Process
  • Protein Ubiquitination
  • SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
  • ERBB2 Signaling Pathway
  • Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
  • Post-translational Protein Modification
  • Calcium Ion Transmembrane Transport
  • Intrinsic Apoptotic Signaling Pathway
Pathways
  • Vif-mediated degradation of APOBEC3G
  • Downregulation of ERBB2 signaling
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes 34 interacting genes: ANAPC11 CBFB CCNDBP1 COMMD1 COPS2 COPS3 COPS4 COPS5 COPS6 COPS7A COPS8 DCUN1D1 DDX10 DEPTOR ELOA ERCC6 GHR GOLGA2 GPS1 PRKACA PTPN5 RBX1 RHOBTB1 RHOBTB2 RHOU RNF7 SMAD2 SMURF1 SOX30 TGFBR1 TRAF6 UBC UBE2F VHL
Entrez ID 8065
HPRD ID 03444
Ensembl ID ENSG00000166266
Uniprot IDs Q93034
PDB IDs 3DPL 3DQV 4JGH 4N9F
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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