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CDK5RAP3
Description
CDK5 regulatory subunit associated protein 3
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleolus
Cytoplasm
Centrosome
Cytosol
Microtubule
Membrane
Protein-containing Complex
Intracellular Membrane-bounded Organelle
Molecular Function
Protein Binding
Protein Kinase Binding
Cyclin Binding
Ubiquitin-like Protein Ligase Binding
Mitogen-activated Protein Kinase Binding
NF-kappaB Binding
MDM2/MDM4 Family Protein Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Protein Phosphorylation
Mitotic G2 DNA Damage Checkpoint
Regulation Of Mitotic Cell Cycle
Brain Development
Cell Proliferation
Regulation Of Phosphatase Activity
Viral Process
Apoptotic Nuclear Changes
Endoplasmic Reticulum Unfolded Protein Response
Positive Regulation Of Protein Ubiquitination
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of MAP Kinase Activity
Negative Regulation Of Protein Kinase Activity By Regulation Of Protein Phosphorylation
Mitotic G2/M Transition Checkpoint
Regulation Of Neuron Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Protein Ufmylation
Negative Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Protein Localization To Nucleus
Positive Regulation Of Signal Transduction By P53 Class Mediator
Negative Regulation Of Cellular Protein Catabolic Process
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Generalized epilepsy (
22949513
)
Metabolite levels (Pyroglutamine) (
23934736
)
Interacting Genes
12 interacting genes:
CDK5R1
CREBBP
CRMP1
DISC1
ESS2
FKBP6
HSPB1
KPNA2
SRPRB
TAB1
TAX1BP3
TSPYL4
Entrez ID
80279
HPRD ID
12190
Ensembl ID
ENSG00000108465
Uniprot IDs
Q96JB5
PDB IDs
Enriched GO Terms of Interacting Partners
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