CALCR

Description		calcitonin receptor
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GO Annotations	Cellular Component	Cell Plasma Membrane Integral Component Of Plasma Membrane Axon Amylin Receptor Complex 1 Amylin Receptor Complex 2 Amylin Receptor Complex 3
	Molecular Function	Amyloid-beta Binding Calcitonin Gene-related Peptide Receptor Activity Calcitonin Receptor Activity Protein Binding Calcitonin Binding Amylin Receptor Activity
	Biological Process	Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Gene Expression Positive Regulation Of Protein Kinase A Signaling Positive Regulation Of Cell Death Positive Regulation Of Peptidyl-serine Phosphorylation Cross-receptor Inhibition Within G Protein-coupled Receptor Heterodimer Response To Glucocorticoid Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of ERK1 And ERK2 Cascade Amylin Receptor Signaling Pathway Response To Amyloid-beta Positive Regulation Of Calcium Ion Import Across Plasma Membrane
Pathways		G alpha (s) signalling events Calcitonin-like ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs		Salmon Calcitonin Pramlintide
Diseases
GWAS		Birth weight ( 23202124) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 28892062 25760438 25673413 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Hip circumference ( 28552196 25673412) Lean body mass ( 28552196 28724990) Weight ( 28552196)
Interacting Genes		9 interacting genes: CALM1 FLNA GPRASP1 GPRASP2 MBL2 RAMP1 RAMP3 SQSTM1 THBS1
Entrez ID		799
HPRD ID		00239
Ensembl ID		ENSG00000004948
Uniprot IDs		A0A0A0MRG0 A0A0C4DG16 P30988
PDB IDs		5II0 5UZ7 6NIY
Enriched GO Terms of Interacting Partners?
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