KDM8

Description		lysine demethylase 8
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytosol
	Molecular Function	Chromatin Binding Endopeptidase Activity Aminopeptidase Activity Oxidoreductase Activity, Acting On Paired Donors, With Incorporation Or Reduction Of Molecular Oxygen, 2-oxoglutarate As One Donor, And Incorporation Of One Atom Each Of Oxygen Into Both Donors Methylated Histone Binding Metal Ion Binding Histone Demethylase Activity (H3-K36 Specific)
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Proteolysis Protein Destabilization Circadian Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Oxidation-reduction Process Histone H3-K36 Demethylation
Pathways
Drugs
Diseases
GWAS		Asthma ( 31619474) Gut microbiota (bacterial taxa) ( 27723756) Night sleep phenotypes ( 27126917)
Interacting Genes		2 interacting genes: MEOX2 PCYT2
Entrez ID		79831
HPRD ID		07836
Ensembl ID		ENSG00000155666
Uniprot IDs		A0A0S2Z5P8 A0A0S2Z5T1 Q8N371
PDB IDs		3UYJ 4AAP 4GAZ 4GJY 4GJZ 4QU1 5FBJ 6AVS 6AX3 6F4M 6F4N 6F4O 6F4P 6F4Q 6F4R 6F4S 6F4T
Enriched GO Terms of Interacting Partners?
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