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C9

Description complement C9
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Membrane Attack Complex
  • Extracellular Space
  • Plasma Membrane
  • Other Organism Cell Membrane
  • Extracellular Exosome
  • Blood Microparticle
Molecular Function
Biological Process
  • Cell Killing
  • Complement Activation, Alternative Pathway
  • Complement Activation, Classical Pathway
  • Cytolysis
  • Regulation Of Complement Activation
  • Protein Homooligomerization
Pathways
  • Terminal pathway of complement
  • Regulation of Complement cascade
Drugs
  • Copper
Diseases
  • Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
GWAS
  • Advanced age-related macular degeneration ( 26691988)
  • Blood protein levels ( 30072576 29875488)
  • Chronic kidney disease ( 20383146)
  • Health literacy ( 31250787)
  • Systemic lupus erythematosus ( 19838195)
Interacting Genes 4 interacting genes: C8A CD59 CLU LAMTOR5
Entrez ID 735
HPRD ID 00408
Ensembl ID ENSG00000113600
Uniprot IDs P02748
PDB IDs 5FMW 6DLW 6H03 6H04
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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