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UBE2V1
Description
ubiquitin conjugating enzyme E2 V1
Image
GO Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Ubiquitin Conjugating Enzyme Complex
Protein-containing Complex
UBC13-UEV1A Complex
Extracellular Exosome
Molecular Function
Protein Binding
Ubiquitin Conjugating Enzyme Activity
Biological Process
Activation Of MAPK Activity
Protein Polyubiquitination
Regulation Of DNA Repair
Postreplication Repair
Regulation Of Transcription, DNA-templated
JNK Cascade
Cell Differentiation
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of NF-kappaB Transcription Factor Activity
Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Interleukin-1-mediated Signaling Pathway
Protein K63-linked Ubiquitination
Pathways
NOD1/2 Signaling Pathway
TICAM1, RIP1-mediated IKK complex recruitment
Downstream TCR signaling
FCERI mediated NF-kB activation
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
activated TAK1 mediates p38 MAPK activation
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
CLEC7A (Dectin-1) signaling
Interleukin-1 signaling
IRAK1 recruits IKK complex
IKK complex recruitment mediated by RIP1
Aggrephagy
Aggrephagy
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes
40 interacting genes:
ARIH2
BIRC2
BIRC3
BIRC8
DTX3
DZIP3
FAM168A
KITLG
MAP3K1
MID1
MKRN3
PELI1
PELI3
PRKN
PSMD14
RC3H1
RC3H2
RNF10
RNF111
RNF14
RNF144A
RNF185
RNF2
RNF5
SMURF1
STUB1
SUMO4
TRAF2
TRAF3IP2
TRAF6
TRIM25
TRIM39
TRIM5
TRIM8
UBC
UBE2N
UBOX5
UBQLN1
XIAP
ZNRF1
Entrez ID
7335
HPRD ID
04294
Ensembl ID
ENSG00000244687
Uniprot IDs
G3V2F7
Q13404
PDB IDs
2A4D
2C2V
2HLW
6D6I
Enriched GO Terms of Interacting Partners
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