C8A

Description		complement C8 alpha chain
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GO Annotations	Cellular Component	Extracellular Region Membrane Attack Complex Extracellular Space Membrane Extracellular Exosome Blood Microparticle
	Molecular Function	Complement Binding Protein-containing Complex Binding
	Biological Process	Immune Response Complement Activation Complement Activation, Alternative Pathway Complement Activation, Classical Pathway Cytolysis Regulation Of Complement Activation
Pathways		Terminal pathway of complement Regulation of Complement cascade
Drugs		Zinc
Diseases		Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
GWAS		Blood protein levels ( 28240269)
Interacting Genes		4 interacting genes: C8B C8G C9 CD59
Entrez ID		731
HPRD ID		00409
Ensembl ID		ENSG00000157131
Uniprot IDs		P07357
PDB IDs		2QOS 2QQH 2RD7 3OJY 6H03 6H04
Enriched GO Terms of Interacting Partners?
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