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HIRA

Description histone cell cycle regulator
Image
GO Annotations Cellular Component
  • HIR Complex
  • Chromosome, Centromeric Region
  • Nuclear Chromatin
  • Nucleus
  • Nucleoplasm
  • PML Body
  • Protein-containing Complex
  • Extracellular Exosome
Molecular Function
  • DNA-binding Transcription Factor Activity
  • Transcription Corepressor Activity
  • Protein Binding
Biological Process
  • Mitotic Sister Chromatid Segregation
  • Osteoblast Differentiation
  • DNA Replication-independent Nucleosome Assembly
  • Transcription, DNA-templated
  • Regulation Of Transcription By RNA Polymerase II
  • Gastrulation
  • Anatomical Structure Morphogenesis
  • Chromatin Silencing At Centromere
  • Regulation Of Chromatin Silencing
  • Muscle Cell Differentiation
Pathways
  • Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS
  • Cognitive decline rate in late mild cognitive impairment ( 26252872)
Interacting Genes 14 interacting genes: ASF1A CCNA2 CDK2 H2BC12 H2BC21 H2BC5 H3-3B HIRIP3 HNRNPD NFU1 OGT PAX7 UBE2I UPF1
Entrez ID 7290
HPRD ID 02583
Ensembl ID ENSG00000100084
Uniprot IDs P54198
PDB IDs 2I32 5YJE
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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