C6

Description		complement C6
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GO Annotations	Cellular Component	Extracellular Region Membrane Attack Complex Extracellular Exosome
	Molecular Function	Protein Binding
	Biological Process	In Utero Embryonic Development Positive Regulation Of Activation Of Membrane Attack Complex Complement Activation Complement Activation, Classical Pathway Cytolysis Regulation Of Complement Activation Innate Immune Response Positive Regulation Of Angiogenesis
Pathways		Terminal pathway of complement Regulation of Complement cascade
Drugs
Diseases		Late complement pathway defects, including the following seven diseases: C5 deficiency; C6 deficiency; C7 deficiency; C8 alpha-chain deficiency; C8 beta-chain deficiency; C8 gamma-chain deficiency; C9 deficiency
GWAS		Blood protein levels ( 28240269) Response to fenofibrate (adiponectin levels) ( 23149075)
Interacting Genes		4 interacting genes: C5 F2 OGA SART3
Entrez ID		729
HPRD ID		01956
Ensembl ID		ENSG00000039537
Uniprot IDs		P13671
PDB IDs		3T5O 4A5W 4E0S 6H03 6H04
Enriched GO Terms of Interacting Partners?
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