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TRPC3

Description transient receptor potential cation channel subfamily C member 3
Image
GO Annotations Cellular Component
  • Cell
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Cation Channel Complex
Molecular Function
  • Calcium Channel Activity
  • Protein Binding
  • Store-operated Calcium Channel Activity
  • Inositol 1,4,5 Trisphosphate Binding
Biological Process
  • Calcium Ion Transport
  • Manganese Ion Transport
  • Single Fertilization
  • Phototransduction
  • Positive Regulation Of Calcium Ion Transport Into Cytosol
  • Platelet Activation
  • Response To ATP
  • Regulation Of Cytosolic Calcium Ion Concentration
  • Response To Calcium Ion
  • Calcium Ion Transmembrane Transport
  • Positive Regulation Of Cardiac Muscle Hypertrophy In Response To Stress
Pathways
  • Effects of PIP2 hydrolysis
  • Elevation of cytosolic Ca2+ levels
  • TRP channels
  • Role of second messengers in netrin-1 signaling
  • MECP2 regulates neuronal receptors and channels
Drugs
Diseases
GWAS
  • Celiac disease and Rheumatoid arthritis ( 26546613)
  • Emphysema imaging phenotypes ( 26030696)
  • Rosacea symptom severity ( 29771307)
Interacting Genes 20 interacting genes: CALM1 FKBP1A GNA11 ITPR1 ITPR3 MX1 NAPA ORAI1 PLCB1 PLCB2 PLCB3 PLCG1 PRKCA PRKG1 SLC8A1 STX3 TRPC1 TRPC6 TRPC7 VAMP2
Entrez ID 7222
HPRD ID 15999
Ensembl ID ENSG00000138741
Uniprot IDs Q13507
PDB IDs 5ZBG 6CUD 6D7L 6DJS
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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