THPO

Description		thrombopoietin
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Signaling Receptor Binding Cytokine Activity Hormone Activity Growth Factor Activity
	Biological Process	Positive Regulation Of Protein Phosphorylation Multicellular Organism Development Cell Proliferation Positive Regulation Of Cell Proliferation Megakaryocyte Development Thrombopoietin-mediated Signaling Pathway Positive Regulation Of MAPK Cascade Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of ERK1 And ERK2 Cascade STAT Cascade Positive Regulation Of Hematopoietic Stem Cell Proliferation
Pathways		Platelet Aggregation (Plug Formation)
Drugs
Diseases
GWAS		Cardiometabolic and hematological traits ( 27668658) Diisocyanate-induced asthma ( 25918132) Platelet count ( 22139419 29403010 20139978 27863252) Plateletcrit ( 27863252)
Interacting Genes		4 interacting genes: APH1A EP300 MPL NUMBL
Entrez ID		7066
HPRD ID		02500
Ensembl ID		ENSG00000090534
Uniprot IDs		A0A3B3ITS0 F8W6L1 P40225 Q5FBX8
PDB IDs		1V7M 1V7N
Enriched GO Terms of Interacting Partners?
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