TGFB3

Description		transforming growth factor beta 3
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Plasma Membrane Cell Surface T-tubule Platelet Alpha Granule Lumen Neuronal Cell Body Intracellular Membrane-bounded Organelle Collagen-containing Extracellular Matrix
	Molecular Function	Type II Transforming Growth Factor Beta Receptor Binding Cytokine Activity Protein Binding Growth Factor Activity Type I Transforming Growth Factor Beta Receptor Binding Type III Transforming Growth Factor Beta Receptor Binding Identical Protein Binding Protein-containing Complex Binding Transforming Growth Factor Beta Binding
	Biological Process	Activation Of MAPK Activity Response To Hypoxia In Utero Embryonic Development Platelet Degranulation Transforming Growth Factor Beta Receptor Signaling Pathway Salivary Gland Morphogenesis Female Pregnancy Aging Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Positive Regulation Of Epithelial To Mesenchymal Transition Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Macrophage Cytokine Production Positive Regulation Of Bone Mineralization BMP Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Mammary Gland Development Response To Progesterone Positive Regulation Of Collagen Biosynthetic Process Response To Laminar Fluid Shear Stress Wound Healing Regulation Of Cell Proliferation Odontogenesis Uterine Wall Breakdown Positive Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Response To Estrogen Ossification Involved In Bone Remodeling Cell-cell Junction Organization Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Lung Alveolus Development Digestive Tract Development Embryonic Neurocranium Morphogenesis Inner Ear Development Positive Regulation Of Protein Secretion Positive Regulation Of Filopodium Assembly Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Cell Division Face Morphogenesis Frontal Suture Morphogenesis Positive Regulation Of SMAD Protein Signal Transduction SMAD Protein Signal Transduction Secondary Palate Development Detection Of Hypoxia Negative Regulation Of Vascular Smooth Muscle Cell Proliferation Regulation Of Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Positive Regulation Of Tight Junction Disassembly
Pathways		Platelet degranulation Molecules associated with elastic fibres ECM proteoglycans
Drugs		1,4-Diethylene Dioxide
Diseases		Arrhythmogenic right ventricular cardiomyopathy (ARVC) Graft-versus-host disease Ossification of the posterior longitudinal ligament of spine (OPLL) Allograft rejection Isolated orofacial clefts, including: Cleft lip with or without cleft palate; Cleft palate
GWAS
Interacting Genes		13 interacting genes: ACVRL1 CCL20 CCN2 CHMP2A ENG FMOD LTBP3 SDC4 TGFB2 TGFBR1 TGFBR2 TGFBR3 VASN
Entrez ID		7043
HPRD ID		01829
Ensembl ID		ENSG00000119699
Uniprot IDs		A5YM40 B3KVH9 P10600
PDB IDs		1KTZ 1TGJ 1TGK 2PJY 3EO1 4UM9
Enriched GO Terms of Interacting Partners?
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