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SLPI

Description secretory leukocyte peptidase inhibitor
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Golgi Apparatus
  • Specific Granule Lumen
  • Collagen-containing Extracellular Matrix
  • Extracellular Exosome
Molecular Function
  • DNA Binding
  • MRNA Binding
  • Endopeptidase Inhibitor Activity
  • Serine-type Endopeptidase Inhibitor Activity
  • Protein Binding
  • Enzyme Binding
Biological Process
  • Immune Response
  • Negative Regulation Of Endopeptidase Activity
  • Antibacterial Humoral Response
  • Negative Regulation Of Protein Binding
  • Response To Lipopolysaccharide
  • Modification Of Morphology Or Physiology Of Other Organism
  • Neutrophil Degranulation
  • Negative Regulation Of Viral Genome Replication
  • Innate Immune Response
Pathways
  • Neutrophil degranulation
Drugs
Diseases
GWAS
  • Bipolar disorder ( 31043756)
  • Blood protein levels ( 30072576 28240269)
Interacting Genes 11 interacting genes: CTSB CTSL CTSS ELANE FAM9B GRN KLK3 MAPK8IP2 PLSCR1 PRSS2 SGTA
Entrez ID 6590
HPRD ID 00121
Ensembl ID ENSG00000124107
Uniprot IDs P03973
PDB IDs 2Z7F 4DOQ
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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