SLC6A4

Description		solute carrier family 6 member 4
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GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Endosome Membrane Endomembrane System Neuron Projection Membrane Raft Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane Serotonergic Synapse
	Molecular Function	Serotonin:sodium Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Syntaxin-1 Binding Cocaine Binding Identical Protein Binding Metal Ion Binding Nitric-oxide Synthase Binding Actin Filament Binding Serotonin Binding
	Biological Process	Response To Hypoxia Transport Response To Nutrient Memory Circadian Rhythm Response To Toxic Substance Positive Regulation Of Gene Expression Positive Regulation Of Serotonin Secretion Monoamine Transport Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Negative Regulation Of Synaptic Transmission, Dopaminergic Response To Estradiol Social Behavior Neurotransmitter Biosynthetic Process Vasoconstriction Response To Drug Sperm Ejaculation Negative Regulation Of Neuron Differentiation Positive Regulation Of Cell Cycle Negative Regulation Of Organ Growth Brain Morphogenesis Serotonin Uptake Transmembrane Transport Cellular Response To Retinoic Acid Cellular Response To CGMP Regulation Of Thalamus Size
Pathways		Serotonin clearance from the synaptic cleft
Drugs		Fluvoxamine Amphetamine Phentermine Tramadol Citalopram Venlafaxine Atomoxetine Amitriptyline Protriptyline Mirtazapine Loxapine Methylphenidate Pethidine Imipramine Fluoxetine Duloxetine Dextromethorphan Nortriptyline Amoxapine Fenfluramine Mazindol Trazodone Verapamil Paroxetine Trimipramine Minaprine Pseudoephedrine Cocaine Dopamine Sertraline Sibutramine Chlorphenamine Doxepin Nefazodone Desipramine Escitalopram Dexfenfluramine Clomipramine Ephedra MMDA Midomafetamine 4-Methoxyamphetamine Methamphetamine Nomifensine Zimelidine Amineptine Bicifadine Milnacipran OPC-14523 CRx-119 Mianserin Tapentadol Desvenlafaxine Dexmethylphenidate Levomilnacipran Butriptyline Vortioxetine Dosulepin Nisoxetine Tianeptine Dasotraline
Diseases
GWAS		Height ( 28552196)
Interacting Genes		5 interacting genes: CALR CANX STX1A VAMP2 YBX1
Entrez ID		6532
HPRD ID		01640
Ensembl ID		ENSG00000108576
Uniprot IDs		B2R7Y7 P31645
PDB IDs		5I6X 5I6Z 5I71 5I73 5I74 5I75 6AWN 6AWO 6AWP 6AWQ 6DZV 6DZW 6DZY 6DZZ
Enriched GO Terms of Interacting Partners?
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