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SLC6A1

Description solute carrier family 6 member 1
Image No pdb structure
GO Annotations Cellular Component
  • Plasma Membrane
  • Cell Surface
  • Membrane
  • Integral Component Of Membrane
  • Cell Junction
  • Axon
  • Neuron Projection
  • GABA-ergic Synapse
  • Integral Component Of Postsynaptic Membrane
  • Integral Component Of Presynaptic Membrane
Molecular Function
  • Gamma-aminobutyric Acid:sodium Symporter Activity
  • Protein Binding
  • Neurotransmitter Binding
  • Identical Protein Binding
  • Metal Ion Binding
Biological Process
  • Transport
  • Chemical Synaptic Transmission
  • Learning
  • Response To Toxic Substance
  • Response To Sucrose
  • Response To Lead Ion
  • Positive Regulation Of Gamma-aminobutyric Acid Secretion
  • Response To Purine-containing Compound
  • Taurine Transport
  • Negative Regulation Of Synaptic Transmission, GABAergic
  • Response To Estradiol
  • Response To Cocaine
  • Response To Calcium Ion
  • Gamma-aminobutyric Acid Import
  • Transmembrane Transport
  • Neurotransmitter Reuptake
Pathways
  • Na+/Cl- dependent neurotransmitter transporters
  • Reuptake of GABA
Drugs
  • Tiagabine
  • Guvacine
Diseases
GWAS
  • Body fat percentage ( 31752434)
  • Conduct disorder (maternal expressed emotions interaction) ( 18846501)
  • Loneliness (linear analysis) ( 27629369)
  • Longitudinal alcohol consumption ( 26081443)
  • Response to Vitamin E supplementation ( 22437554)
Interacting Genes 1 interacting genes: STX1A
Entrez ID 6529
HPRD ID 00664
Ensembl ID ENSG00000157103
Uniprot IDs A0A2R8Y4I3 B7Z3C5 P30531
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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