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SFTPB

Description surfactant protein B
Image
GO Annotations Cellular Component
  • Extracellular Region
  • Extracellular Space
  • Nucleoplasm
  • Lysosome
  • Multivesicular Body
  • Endoplasmic Reticulum Membrane
  • Lamellar Body
  • Clathrin-coated Endocytic Vesicle
  • Alveolar Lamellar Body
  • Multivesicular Body Lumen
Molecular Function
Biological Process
  • Sphingolipid Metabolic Process
  • Respiratory Gaseous Exchange
  • Animal Organ Morphogenesis
  • Cellular Protein Metabolic Process
Pathways
  • Surfactant metabolism
  • Defective pro-SFTPB causes pulmonary surfactant metabolism dysfunction 1 (SMDP1) and respiratory distress syndrome (RDS)
  • Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5)
  • Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)
Drugs
Diseases
  • Pulmonary surfactant metabolism dysfunction (SMDP)
GWAS
  • Blood protein levels ( 30072576)
Interacting Genes 2 interacting genes: CTSH GRPEL1
Entrez ID 6439
HPRD ID 01523
Ensembl ID ENSG00000168878
Uniprot IDs D6W5L6 P07988
PDB IDs 1DFW 1KMR 1RG3 1RG4 1SSZ 2DWF 2JOU 2M0H 2M1T
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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