SEL1L

Description		SEL1L adaptor subunit of ERAD E3 ubiquitin ligase
Image		No pdb structure
GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase Complex Hrd1p Ubiquitin Ligase ERAD-L Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Derlin-1 Retrotranslocation Complex Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	Protein Binding
	Biological Process	Triglyceride Metabolic Process Notch Signaling Pathway Protein Secretion Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol ERAD Pathway Protein Stabilization Transmembrane Transport Endoplasmic Reticulum Mannose Trimming
Pathways		Pre-NOTCH Processing in Golgi ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants that don't undergo autocatalytic processing are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Cadmium levels ( 26025379) Intraocular pressure ( 29617998) Night sleep phenotypes ( 27126917) Periodontal disease-related phenotype (Socransky) ( 24347629)
Interacting Genes		2 interacting genes: HYOU1 RPL6
Entrez ID		6400
HPRD ID		07532
Ensembl ID		ENSG00000071537
Uniprot IDs		Q3ZCU6 Q9UBV2
PDB IDs
Enriched GO Terms of Interacting Partners?
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