THADA

Description		THADA armadillo repeat containing
Image
GO Annotations	Cellular Component	Cytosol Cytoplasmic Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding
	Biological Process	TRNA Methylation Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Lipid Homeostasis Negative Regulation Of Calcium-transporting ATPase Activity Adaptive Thermogenesis
Pathways		tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		Alopecia areata ( 25337690) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Coronary artery disease ( 29212778) Crohn's disease ( 28067908 21102463) Diabetes in response to antihypertensive drug treatment (treatment strategy interaction) ( 27670767) Diastolic blood pressure ( 31469255) DNA methylation (variation) ( 23725790) Estimated glomerular filtration rate ( 31015462) Glomerular filtration rate (creatinine) ( 26831199) Glucose homeostasis traits ( 25524916) Granulocyte count ( 27863252) Granulocyte percentage of myeloid white cells ( 27863252) Hair morphology ( 19896111) Heel bone mineral density ( 30598549 28869591) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Intraocular pressure ( 29617998 29785010 31959993 30054594) Latent autoimmune diabetes ( 30254083) Male-pattern baldness ( 27182965 28196072) Mean corpuscular hemoglobin ( 27863252) Mean corpuscular volume ( 27863252) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (beta blocking agents) ( 31015401) Medication use (drugs used in diabetes) ( 31015401) Mitochondrial DNA levels ( 25240745) Multiple sclerosis ( 22190364) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Orofacial clefts ( 20023658 22863734) Platelet count ( 22139419) Plateletcrit ( 27863252) Polycystic ovary syndrome ( 30566500 26416764 21151128) Prostate cancer ( 31562322 19767753) Response to amphetamines ( 22952603) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Systolic blood pressure ( 30224653) Triglycerides ( 30275531) Type 2 diabetes ( 22885922 18372903 30054458 29358691 30297969 29632382 28869590) Type 2 diabetes (adjusted for BMI) ( 29632382) Viral capsid antigen IgG seropositivity ( 29868224)
Interacting Genes		1 interacting genes: USHBP1
Entrez ID		63892
HPRD ID		18177
Ensembl ID		ENSG00000115970
Uniprot IDs		Q6YHU6
PDB IDs		5T6Y
Enriched GO Terms of Interacting Partners?
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