BGLAP

Description		bone gamma-carboxyglutamate protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Lumen Rough Endoplasmic Reticulum Golgi Lumen Dendrite Vesicle Perikaryon
	Molecular Function	Structural Molecule Activity Calcium Ion Binding Structural Constituent Of Bone Hydroxyapatite Binding
	Biological Process	Skeletal System Development Ossification Osteoblast Differentiation Osteoblast Development ER To Golgi Vesicle-mediated Transport Cell Adhesion Cell Aging Response To Mechanical Stimulus Response To Gravity Response To Zinc Ion Response To Activity Bone Mineralization Regulation Of Bone Mineralization Response To Vitamin K Response To Vitamin D Response To Testosterone Response To Hydroxyisoflavone Odontogenesis Response To Estrogen Regulation Of Bone Resorption Response To Ethanol Regulation Of Osteoclast Differentiation Response To Glucocorticoid Bone Development Cellular Response To Vitamin D Cellular Response To Growth Factor Stimulus Regulation Of Cellular Response To Insulin Stimulus
Pathways		Gamma-carboxylation of protein precursors Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus Removal of aminoterminal propeptides from gamma-carboxylated proteins RUNX2 regulates osteoblast differentiation
Drugs		Menadione Phylloquinone Gamma-Carboxy-Glutamic Acid Gallium nitrate
Diseases
GWAS		Estimated glomerular filtration rate ( 30604766) Mean corpuscular hemoglobin concentration ( 20139978) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) White matter hyperintensity burden ( 25663218)
Interacting Genes		5 interacting genes: CTSB CTSD CTSH CTSS GGCX
Entrez ID		632
HPRD ID		00205
Ensembl ID		ENSG00000242252
Uniprot IDs		P02818
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?