SAA1

Description		serum amyloid A1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Cytoplasmic Microtubule High-density Lipoprotein Particle Extracellular Exosome Endocytic Vesicle Lumen
	Molecular Function	G Protein-coupled Receptor Binding Heparin Binding Chemoattractant Activity
	Biological Process	Activation Of MAPK Activity Receptor-mediated Endocytosis Acute-phase Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cytokine-mediated Signaling Pathway Platelet Activation Neutrophil Chemotaxis Cellular Protein Metabolic Process Innate Immune Response Positive Regulation Of Cell Adhesion Macrophage Chemotaxis Lymphocyte Chemotaxis Regulation Of Protein Secretion Positive Regulation Of Cytokine Secretion Positive Regulation Of Interleukin-1 Secretion Negative Regulation Of Inflammatory Response Positive Chemotaxis Cell Chemotaxis
Pathways		Scavenging by Class B Receptors G alpha (q) signalling events G alpha (i) signalling events Formyl peptide receptors bind formyl peptides and many other ligands TAK1 activates NFkB by phosphorylation and activation of IKKs complex Interleukin-4 and Interleukin-13 signaling Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling TRAF6 mediated NF-kB activation Amyloid fiber formation
Drugs		Human Serum Albumin
Diseases
GWAS		Amyloid A serum levels ( 21124955) Blood protein levels ( 30072576 29875488 28240269) Rosacea symptom severity ( 29771307)
Interacting Genes		10 interacting genes: COL4A1 COL4A2 COL4A3 COL4A4 FPR1 GLP1R GNG5 LAMA1 SELENOS VKORC1
Entrez ID		6288
HPRD ID		00097
Ensembl ID		ENSG00000173432
Uniprot IDs		P0DJI8
PDB IDs		4IP8 4IP9 6MST
Enriched GO Terms of Interacting Partners?
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