S100A12

Description		S100 calcium binding protein A12
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GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm Cytosol Cytoskeleton Plasma Membrane Secretory Granule Lumen
	Molecular Function	Copper Ion Binding Calcium Ion Binding Protein Binding Zinc Ion Binding RAGE Receptor Binding
	Biological Process	Monocyte Chemotaxis Xenobiotic Metabolic Process Inflammatory Response Neutrophil Chemotaxis Killing Of Cells Of Other Organism Defense Response To Bacterium Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Neutrophil Degranulation Positive Regulation Of MAP Kinase Activity Innate Immune Response Mast Cell Activation Cytokine Secretion Positive Regulation Of Inflammatory Response Defense Response To Fungus Positive Regulation Of NF-kappaB Transcription Factor Activity Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Pathways		TAK1 activates NFkB by phosphorylation and activation of IKKs complex Neutrophil degranulation Advanced glycosylation endproduct receptor signaling Advanced glycosylation endproduct receptor signaling TRAF6 mediated NF-kB activation
Drugs		Olopatadine Amlexanox
Diseases
GWAS		Asthma ( 31619474) Blood protein levels ( 30072576) Matrix metalloproteinase-8 levels ( 29212897)
Interacting Genes		3 interacting genes: AGER CACYBP RBX1
Entrez ID		6283
HPRD ID		04383
Ensembl ID		ENSG00000163221
Uniprot IDs		P80511
PDB IDs		1E8A 1GQM 1ODB 2M9G 2WC8 2WCB 2WCE 2WCF
Enriched GO Terms of Interacting Partners?
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