RPL11

Description		ribosomal protein L11
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GO Annotations	Cellular Component	Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Cytosolic Large Ribosomal Subunit Protein-containing Complex Polysomal Ribosome Extracellular Exosome
	Molecular Function	RNA Binding Structural Constituent Of Ribosome Protein Binding 5S RRNA Binding Ubiquitin Protein Ligase Binding Ubiquitin Ligase Inhibitor Activity
	Biological Process	Ribosomal Large Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation RRNA Processing Translation Translational Initiation Protein Targeting SRP-dependent Cotranslational Protein Targeting To Membrane Positive Regulation Of Gene Expression Viral Transcription Positive Regulation Of Protein Binding Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Localization To Nucleus Ribosomal Large Subunit Biogenesis Protein Stabilization Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Ubiquitin Protein Ligase Activity Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Neddylation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Alpha-Hydroxy-Beta-Phenyl-Propionic Acid Anisomycin Puromycin
Diseases		Diamond-Blackfan anemia (DBA)
GWAS
Interacting Genes		19 interacting genes: APP ARFGAP1 BLMH CAMK2B CDKN2A HP HSPB2 IGF1R KRT40 KRTAP10-7 LIG4 MDM2 PAIP2 PML SENP1 STAT3 TIGAR TP73 UBE2I
Entrez ID		6135
HPRD ID		10364
Ensembl ID		ENSG00000142676
Uniprot IDs		P62913 Q5VVD0
PDB IDs		4UG0 4V6X 4XXB 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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