ASH1L

Description		ASH1 like histone lysine methyltransferase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Golgi Apparatus Bicellular Tight Junction
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Histone Methyltransferase Activity (H3-K4 Specific) Metal Ion Binding Histone Methyltransferase Activity (H3-K9 Specific) Histone Methyltransferase Activity (H3-K36 Specific)
	Biological Process	Skeletal System Development Negative Regulation Of Acute Inflammatory Response DNA Packaging Transcription By RNA Polymerase II Cell-cell Signaling Single Fertilization Post-embryonic Development Flagellated Sperm Motility Interleukin-6 Production Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of MAPK Cascade Positive Regulation Of Transcription By RNA Polymerase II Decidualization Histone H3-K9 Methylation Histone H3-K4 Methylation Uterus Morphogenesis Histone H3-K36 Dimethylation Tarsal Gland Development Uterine Gland Development
Pathways		PKMTs methylate histone lysines
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Chronic periodontitis (mean interproximal clinical attachment level) ( 27601451) Crohn's disease ( 28067908) Dementia with Lewy bodies ( 31065058) Inflammatory bowel disease ( 28067908) Nickel levels ( 26025379) Non-cardia gastric cancer ( 26701879)
Interacting Genes		2 interacting genes: H3C1 SMAD7
Entrez ID		55870
HPRD ID		06416
Ensembl ID		ENSG00000116539
Uniprot IDs		Q9NR48
PDB IDs		3MQM 3OPE 4YNM 4YNP 4YPA 4YPE 4YPU 6AGO 6INE
Enriched GO Terms of Interacting Partners?
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