KDM3A

Description		lysine demethylase 3A
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Membrane
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Iron Ion Binding Protein Binding Chromatin DNA Binding Histone Demethylase Activity (H3-K9 Specific) Androgen Receptor Binding Dioxygenase Activity
	Biological Process	Regulation Of Transcription, DNA-templated Spermatid Nucleus Elongation Hormone-mediated Signaling Pathway Androgen Receptor Signaling Pathway Histone H3-K9 Demethylation Histone H3-K9 Dimethylation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Formaldehyde Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Oxidation-reduction Process Positive Regulation Of Cold-induced Thermogenesis Cellular Response To Leukemia Inhibitory Factor Regulation Of Stem Cell Population Maintenance Regulation Of Stem Cell Differentiation
Pathways		HDMs demethylate histones NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs
Diseases
GWAS		Atrial fibrillation ( 29892015) Glomerular filtration rate in chronic kidney disease ( 26420894) Ovarian cancer ( 30557369)
Interacting Genes		6 interacting genes: ETV2 H3C14 MRTFA MRTFB MYOCD RIPK2
Entrez ID		55818
HPRD ID		11054
Ensembl ID		ENSG00000115548
Uniprot IDs		Q9Y4C1
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?