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PRKAB1

Description protein kinase AMP-activated non-catalytic subunit beta 1
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Cytosol
  • Nucleotide-activated Protein Kinase Complex
Molecular Function
  • Protein Kinase Activity
  • AMP-activated Protein Kinase Activity
  • Protein Binding
  • Protein Kinase Binding
  • Protein-containing Complex Binding
Biological Process
  • Protein Phosphorylation
  • Fatty Acid Biosynthetic Process
  • Cell Cycle Arrest
  • Signal Transduction
  • Positive Regulation Of Gene Expression
  • Macroautophagy
  • Regulation Of Macroautophagy
  • Nail Development
  • Regulation Of Catalytic Activity
  • Positive Regulation Of Cold-induced Thermogenesis
  • Regulation Of Signal Transduction By P53 Class Mediator
Pathways
  • Translocation of SLC2A4 (GLUT4) to the plasma membrane
  • Macroautophagy
  • Activation of PPARGC1A (PGC-1alpha) by phosphorylation
  • Energy dependent regulation of mTOR by LKB1-AMPK
  • TP53 Regulates Metabolic Genes
  • Regulation of TP53 Activity through Phosphorylation
  • Lipophagy
  • Activation of AMPK downstream of NMDARs
Drugs
  • Adenosine monophosphate
  • Metformin
  • Acetylsalicylic acid
Diseases
GWAS
  • Inflammatory bowel disease ( 26192919)
  • Ulcerative colitis ( 26192919)
Interacting Genes 12 interacting genes: ACACA AGL APP F10 GRB2 MAP3K7 MAPK6 NDUFA7 PRKAA1 PRKAA2 PRKAG1 PRKAG2
Entrez ID 5564
HPRD ID 04116
Ensembl ID ENSG00000111725
Uniprot IDs A0A024RBN1 Q9Y478
PDB IDs 4CFE 4CFF 4ZHX 5EZV 5ISO 6B1U 6C9F 6C9G 6C9H 6C9J
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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