AVPR1A

Description		arginine vasopressin receptor 1A
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GO Annotations	Cellular Component	Cell Endosome Plasma Membrane Integral Component Of Plasma Membrane Endocytic Vesicle
	Molecular Function	G Protein-coupled Receptor Activity Vasopressin Receptor Activity Protein Kinase C Binding Protein Binding Peptide Hormone Binding V1A Vasopressin Receptor Binding Peptide Binding
	Biological Process	Regulation Of Systemic Arterial Blood Pressure By Vasopressin Maternal Aggressive Behavior Positive Regulation Of Systemic Arterial Blood Pressure Generation Of Precursor Metabolites And Energy G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Female Receptivity Grooming Behavior Blood Circulation Positive Regulation Of Cell Proliferation Positive Regulation Of Heart Rate Positive Regulation Of Glutamate Secretion Myotube Differentiation Calcium-mediated Signaling Telencephalon Development Positive Regulation Of Cell Growth Positive Regulation Of Prostaglandin Biosynthetic Process Positive Regulation Of Cellular PH Reduction Cellular Response To Hormone Stimulus Social Behavior Positive Regulation Of Renal Sodium Excretion Cellular Response To Water Deprivation Maternal Behavior Sperm Ejaculation Penile Erection Positive Regulation Of Vasoconstriction Response To Corticosterone Negative Regulation Of Transmission Of Nerve Impulse
Pathways		Vasopressin-like receptors G alpha (q) signalling events Defective AVP does not bind AVPR1A,B and causes neurohypophyseal diabetes insipidus (NDI)
Drugs		Desmopressin Vasopressin Felypressin Conivaptan Terlipressin PH-284 Tolvaptan Relcovaptan
Diseases
GWAS		Chronotype ( 30696823) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Hippocampal volume ( 29860282) Morning person ( 30696823) Type 2 diabetes ( 31049640)
Interacting Genes		3 interacting genes: AVP GRK5 PRKCA
Entrez ID		552
HPRD ID		02894
Ensembl ID		ENSG00000166148
Uniprot IDs		P37288 X5D2B0
PDB IDs		1YTV
Enriched GO Terms of Interacting Partners?
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