RNF186

Description		ring finger protein 186
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Protein K29-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Protein K63-linked Ubiquitination Protein Localization To Mitochondrion
Pathways
Drugs
Diseases
GWAS		Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Inflammatory bowel disease ( 28067908) Ulcerative colitis ( 28067908 20228799 19122664 23511034)
Interacting Genes		2 interacting genes: UBE2D2 UBE2H
Entrez ID		54546
HPRD ID		07885
Ensembl ID		ENSG00000178828
Uniprot IDs		Q9NXI6
PDB IDs
Enriched GO Terms of Interacting Partners?
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