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FBXW5

Description F-box and WD repeat domain containing 5
Image No pdb structure
GO Annotations Cellular Component
  • Cytoplasm
  • Cytosol
  • SCF Ubiquitin Ligase Complex
  • Cul4-RING E3 Ubiquitin Ligase Complex
Molecular Function
  • Protein Binding
  • Protein Kinase Binding
Biological Process
  • Protein Polyubiquitination
  • Regulation Of Mitotic Nuclear Division
  • Regulation Of Centrosome Duplication
  • Protein Ubiquitination
  • SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
  • Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
  • Post-translational Protein Modification
Pathways
  • Association of TriC/CCT with target proteins during biosynthesis
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
  • Blood protein levels ( 29875488)
  • Heel bone mineral density ( 30598549)
Interacting Genes 19 interacting genes: ADAMTSL4 FAM168A KRT31 KRT40 KRTAP10-3 KRTAP10-8 KRTAP4-12 KRTAP9-4 MDFI MYB NLK NOTCH2NLA S100B SASS6 SEC23B SKP1 TRIM27 TSC2 UBE2R2
Entrez ID 54461
HPRD ID 10955
Ensembl ID ENSG00000159069
Uniprot IDs A0A024R8H7 Q969U6
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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