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PLD1

Description phospholipase D1
Image No pdb structure
GO Annotations Cellular Component
  • Golgi Membrane
  • Lysosomal Membrane
  • Endosome
  • Endoplasmic Reticulum Membrane
  • Golgi Apparatus
  • Plasma Membrane
  • Membrane
  • Apical Plasma Membrane
  • Endocytic Vesicle
  • Late Endosome Membrane
  • Specific Granule Membrane
  • Perinuclear Region Of Cytoplasm
  • Tertiary Granule Membrane
  • Cholinergic Synapse
Molecular Function
  • Phospholipase D Activity
  • Protein Binding
  • Phosphatidylinositol Binding
  • N-acylphosphatidylethanolamine-specific Phospholipase D Activity
Biological Process
  • Phosphatidic Acid Biosynthetic Process
  • Chemotaxis
  • Small GTPase Mediated Signal Transduction
  • Ras Protein Signal Transduction
  • Lipid Catabolic Process
  • Regulation Of Microvillus Assembly
  • Neutrophil Degranulation
  • Positive Regulation Of Translation
  • Inositol Lipid-mediated Signaling
  • Cell Motility
  • Regulation Of Synaptic Vesicle Cycle
Pathways
  • Synthesis of PG
  • Synthesis of PA
  • Role of phospholipids in phagocytosis
  • Neutrophil degranulation
Drugs
  • Choline
  • LAX-101
Diseases
GWAS
  • Cerebrospinal fluid AB1-42 levels ( 29274321)
  • Red cell distribution width ( 27863252 28957414)
Interacting Genes 26 interacting genes: ACTA1 ACTB ACTG1 ARF1 ARF6 ARIH1 BIN1 CAV1 CDC42 EGFR EGLN1 HIF1A PEA15 PIP5K1A PKN1 PKN3 PRKCA RAC1 RALA RHEB RHOA RHOG SNCA SRC STXBP1 VHL
Entrez ID 5337
HPRD ID 03855
Ensembl ID ENSG00000075651
Uniprot IDs Q13393 Q59EA4
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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