DDX41

Description		DEAD-box helicase 41
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GO Annotations	Cellular Component	Nucleus Spliceosomal Complex Endoplasmic Reticulum Cytosol Membrane Catalytic Step 2 Spliceosome
	Molecular Function	DNA Binding RNA Binding RNA Helicase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Apoptotic Process Cell Proliferation Cell Differentiation Positive Regulation Of Type I Interferon Production Cellular Response To Interferon-beta Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus
Pathways		STING mediated induction of host immune responses Regulation of innate immune responses to cytosolic DNA IRF3-mediated induction of type I IFN
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: CEP70 CHAF1A KLC2 SIAH1 TUBG1
Entrez ID		51428
HPRD ID		10490
Ensembl ID		ENSG00000183258
Uniprot IDs		B3KRK2 Q9UJV9
PDB IDs		2P6N 5GVR 5GVS 5H1Y
Enriched GO Terms of Interacting Partners?
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