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ZBTB7B
Description
zinc finger and BTB domain containing 7B
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Molecular Function
RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding
Proximal Promoter Sequence-specific DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Protein Homodimerization Activity
Histone Deacetylase Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
NK T Cell Differentiation
Transcription By RNA Polymerase II
Ectoderm Development
Lactation
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Histone Deacetylation
Response To Insulin
Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation
Negative Regulation Of CD8-positive, Alpha-beta T Cell Differentiation
Positive Regulation Of Insulin Receptor Signaling Pathway
Negative Regulation Of NK T Cell Proliferation
Regulation Of Transcription Involved In Cell Fate Commitment
Interleukin-17 Secretion
Positive Regulation Of Brown Fat Cell Differentiation
Positive Regulation Of Cold-induced Thermogenesis
Adaptive Thermogenesis
Negative Regulation Of T-helper 17 Cell Differentiation
Positive Regulation Of SREBP Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Basal cell carcinoma (
31174203
)
Bipolar disorder (
31043756
)
Birth weight (
27680694
)
Body fat distribution (leg fat ratio) (
30664634
)
Body fat distribution (trunk fat ratio) (
30664634
)
Body mass index (
29273807
)
Keratinocyte cancer (MTAG) (
31174203
)
Multiple sclerosis (
31604244
)
Prostate cancer (
23535732
)
Waist-to-hip ratio adjusted for BMI (additive genetic model) (
30778226
)
Interacting Genes
19 interacting genes:
BCL6
CRBN
EP300
GRAP2
GRB2
IMP4
KPNA2
MORF4L2
NCK2
NDN
PIN1
RELA
RPL9
SH3KBP1
SH3YL1
SORBS3
SYTL4
ZBTB5
ZNF277
Entrez ID
51043
HPRD ID
09625
Ensembl ID
ENSG00000160685
Uniprot IDs
O15156
PDB IDs
Enriched GO Terms of Interacting Partners
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