DERL2

Description		derlin 2
Image		No pdb structure
GO Annotations	Cellular Component	Hrd1p Ubiquitin Ligase ERAD-L Complex Early Endosome Late Endosome Endoplasmic Reticulum Signal Recognition Particle Receptor Complex Endoplasmic Reticulum Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane Endoplasmic Reticulum Quality Control Compartment Signal Recognition Particle
	Molecular Function	Protein Binding Misfolded Protein Binding Ubiquitin-specific Protease Binding
	Biological Process	Suckling Behavior Positive Regulation Of Cell Proliferation Viral Process Positive Regulation Of Cell Growth Ubiquitin-dependent ERAD Pathway Endoplasmic Reticulum Unfolded Protein Response Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Endoplasmic Reticulum Mannose Trimming
Pathways		ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants that don't undergo autocatalytic processing are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Asparaginase hypersensitivity in acute lymphoblastic leukemia ( 25987655)
Interacting Genes		6 interacting genes: KRTAP10-3 KRTAP10-7 KRTAP10-8 LMNA MELTF SERPINA1
Entrez ID		51009
HPRD ID		16796
Ensembl ID		ENSG00000072849
Uniprot IDs		I3L3R8 Q9GZP9
PDB IDs
Enriched GO Terms of Interacting Partners?
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