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CNOT4

Description CCR4-NOT transcription complex subunit 4
Image
GO Annotations Cellular Component
  • Nucleus
  • Cytosol
  • CCR4-NOT Complex
Molecular Function
  • RNA Binding
  • Ubiquitin-protein Transferase Activity
  • Protein Binding
  • Metal Ion Binding
Biological Process
  • Nuclear-transcribed MRNA Poly(A) Tail Shortening
  • Ubiquitin-dependent Protein Catabolic Process
  • DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
  • Protein Ubiquitination
  • Regulation Of Megakaryocyte Differentiation
  • Protein Autoubiquitination
Pathways
  • Deadenylation of mRNA
  • TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain
Drugs
Diseases
GWAS
  • Heel bone mineral density ( 30598549)
  • Household income (MTAG) ( 31844048)
  • Numerical cognitive ability ( 31620175)
Interacting Genes 18 interacting genes: CNOT1 CNOT2 CNOT3 CNOT6 CNOT8 CNOT9 EP300 KDM5C RBM15 UBE2B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2N UBE2W
Entrez ID 4850
HPRD ID 05369
Ensembl ID ENSG00000080802
Uniprot IDs A0A024R776 A0A024R781 A0A024R785 O95628
PDB IDs 1E4U 1UR6
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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