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NDUFA1

Description NADH:ubiquinone oxidoreductase subunit A1
Image
GO Annotations Cellular Component
  • Mitochondrion
  • Mitochondrial Inner Membrane
  • Mitochondrial Respiratory Chain Complex I
  • Cytosol
  • Integral Component Of Membrane
  • Mitochondrial Membrane
Molecular Function
  • NADH Dehydrogenase (ubiquinone) Activity
Biological Process
  • Mitochondrial Electron Transport, NADH To Ubiquinone
  • Mitochondrial Respiratory Chain Complex I Assembly
Pathways
  • Respiratory electron transport
  • Complex I biogenesis
Drugs
  • NADH
Diseases
  • Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS
Interacting Genes 3 interacting genes: GOLGB1 TRIM55 TRIM63
Entrez ID 4694
HPRD ID 02093
Ensembl ID ENSG00000125356
Uniprot IDs O15239 Q6IBB5
PDB IDs 5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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