MUTYH

Description		mutY DNA glycosylase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion
	Molecular Function	Purine-specific Mismatch Base Pair DNA N-glycosylase Activity Protein Binding DNA N-glycosylase Activity Oxidized Purine DNA Binding MutLalpha Complex Binding MutLbeta Complex Binding MutSalpha Complex Binding MutSbeta Complex Binding 8-oxo-7,8-dihydroguanine DNA N-glycosylase Activity Adenine/guanine Mispair Binding Metal Ion Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	DNA Repair Base-excision Repair Mismatch Repair Depurination
Pathways
Drugs
Diseases		Familial adenomatous polyposis
GWAS		Composite immunoglobulin trait (IgA/IgM) ( 28628107)
Interacting Genes		9 interacting genes: AGTRAP APEX1 LMNA LRSAM1 MSH6 PCNA RPA1 RPA4 SIRT6
Entrez ID		4595
HPRD ID		05380
Ensembl ID		ENSG00000132781
Uniprot IDs		D3DPZ6 E5KP25 E5KP26 E5KP27 E5KP28 E9PM53 Q9UIF7
PDB IDs		1X51 3N5N
Enriched GO Terms of Interacting Partners?
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