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M6PR

Description mannose-6-phosphate receptor, cation dependent
Image
GO Annotations Cellular Component
  • Lysosomal Membrane
  • Endosome
  • Late Endosome
  • Trans-Golgi Network
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • Membrane
  • Transport Vesicle
  • Clathrin-coated Vesicle Membrane
  • Trans-Golgi Network Membrane
  • Perinuclear Region Of Cytoplasm
Molecular Function
  • Transmembrane Signaling Receptor Activity
  • Protein Binding
  • Protein Domain Specific Binding
  • Retromer Complex Binding
Biological Process
  • Protein Targeting To Lysosome
  • Receptor-mediated Endocytosis
  • Lysosomal Transport
  • Endosome To Lysosome Transport
  • Secretion Of Lysosomal Enzymes
  • Membrane Organization
Pathways
  • Lysosome Vesicle Biogenesis
  • Retrograde transport at the Trans-Golgi-Network
  • Cargo recognition for clathrin-mediated endocytosis
  • Clathrin-mediated endocytosis
Drugs
  • Alglucosidase alfa
  • 1-3 Sugar Ring of Pentamannosyl 6-Phosphate
  • alpha-D-mannose 6-phosphate
Diseases
GWAS
  • Sjögren's syndrome ( 28076899)
  • Total cholesterol levels ( 30275531)
Interacting Genes 6 interacting genes: GGA1 GGA2 GGA3 JUN PLIN3 REN
Entrez ID 4074
HPRD ID 01106
Ensembl ID ENSG00000003056
Uniprot IDs F5GX30 P20645
PDB IDs 1JUQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025

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