LRP4

Description		LDL receptor related protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Postsynaptic Density Integral Component Of Membrane Dendrite Neuromuscular Junction Neuronal Cell Body Plasma Membrane Raft Synaptic Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Receptor Tyrosine Kinase Binding Apolipoprotein Binding Protein Homodimerization Activity Scaffold Protein Binding
	Biological Process	Kidney Development Hair Follicle Development Endocytosis Dorsal/ventral Pattern Formation Proximal/distal Pattern Formation Wnt Signaling Pathway Negative Regulation Of Ossification Odontogenesis Of Dentin-containing Tooth Embryonic Digit Morphogenesis Dendrite Morphogenesis Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Axonogenesis Synapse Organization Synaptic Growth At Neuromuscular Junction Limb Development Skeletal Muscle Acetylcholine-gated Channel Clustering Negative Regulation Of Canonical Wnt Signaling Pathway Postsynaptic Membrane Assembly Presynaptic Membrane Assembly Amyloid-beta Clearance By Cellular Catabolic Process Positive Regulation Of Presynaptic Membrane Organization Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways		ECM proteoglycans
Drugs
Diseases		Cenani-Lenz syndactyly syndrome
GWAS		Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Bone mineral density (hip) ( 19079262) D-dimer levels ( 21502573) General risk tolerance (MTAG) ( 30643258) HDL cholesterol ( 24097068 20686565) HDL cholesterol levels ( 28334899) Heel bone mineral density ( 30598549 28869591) Intraocular pressure ( 29617998) Mood instability ( 31168069) Pre-treatment viral load in HIV-1 infection ( 31219150) Reaction time ( 29844566) Systolic blood pressure ( 30224653) Urate levels ( 31578528) Venous thromboembolism ( 31420334)
Interacting Genes		1 interacting genes: WHRN
Entrez ID		4038
HPRD ID		18517
Ensembl ID		ENSG00000134569
Uniprot IDs		O75096
PDB IDs
Enriched GO Terms of Interacting Partners?
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