LNPEP

Description		leucyl and cystinyl aminopeptidase
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Lysosomal Membrane Cytosol Integral Component Of Plasma Membrane Membrane Cytoplasmic Vesicle Membrane Early Endosome Lumen Perinuclear Region Of Cytoplasm
	Molecular Function	Aminopeptidase Activity Protein Binding Metallopeptidase Activity Zinc Ion Binding Peptide Binding Metalloaminopeptidase Activity
	Biological Process	Protein Polyubiquitination Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Proteolysis Cell-cell Signaling Female Pregnancy Protein Catabolic Process Peptide Catabolic Process SMAD Protein Signal Transduction Negative Regulation Of Cold-induced Thermogenesis
Pathways		Endosomal/Vacuolar pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Acute anterior uveitis (with or without ankylosing spondylitis) ( 25200001) Ankylosing spondylitis ( 23749187) Birdshot chorioretinopathy ( 24957906) Blood protein levels ( 28240269) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761)
Interacting Genes		8 interacting genes: FATE1 FHOD1 REL SLC2A4 SMAD9 TCF4 TNKS TNKS2
Entrez ID		4012
HPRD ID		01041
Ensembl ID		ENSG00000113441
Uniprot IDs		Q9UIQ6
PDB IDs		4P8Q 4PJ6 4Z7I 5C97 5JHQ 5MJ6
Enriched GO Terms of Interacting Partners?
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