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LBR

Description lamin B receptor
Image
GO Annotations Cellular Component
  • Nucleus
  • Nuclear Envelope
  • Nuclear Inner Membrane
  • Integral Component Of Nuclear Inner Membrane
  • Cytoplasm
  • Endoplasmic Reticulum Membrane
  • Membrane
  • Integral Component Of Membrane
  • Nuclear Membrane
Molecular Function
  • DNA Binding
  • RNA Binding
  • Protein Binding
  • Lamin Binding
  • Oxidoreductase Activity, Acting On The CH-CH Group Of Donors
  • Delta14-sterol Reductase Activity
  • Chromo Shadow Domain Binding
  • NADPH Binding
Biological Process
  • Cholesterol Biosynthetic Process
  • Sterol Biosynthetic Process
  • Neutrophil Differentiation
  • Oxidation-reduction Process
Pathways
  • Cholesterol biosynthesis
  • Initiation of Nuclear Envelope (NE) Reformation
  • Regulation of MECP2 expression and activity
Drugs
Diseases
  • HEM skeletal dysplasia; Greenberg dysplasia
  • Pelger-Huet anomaly
GWAS
  • Delirium ( 29631748)
Interacting Genes 11 interacting genes: AKAP8L CBX3 CBX5 FNBP4 H4C14 LMNB1 MECP2 PRM1 SRPK1 SRPK2 YWHAG
Entrez ID 3930
HPRD ID 02488
Ensembl ID ENSG00000143815
Uniprot IDs Q14739
PDB IDs 2DIG
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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