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ITPK1

Description inositol-tetrakisphosphate 1-kinase
Image
GO Annotations Cellular Component
  • Cytoplasm
  • Cytosol
  • Apical Plasma Membrane
Molecular Function
  • Magnesium Ion Binding
  • Inositol Tetrakisphosphate 6-kinase Activity
  • Catalytic Activity
  • ATP Binding
  • Hydrolase Activity
  • Isomerase Activity
  • Inositol Tetrakisphosphate 1-kinase Activity
  • Inositol-1,3,4-trisphosphate 6-kinase Activity
  • Inositol-1,3,4-trisphosphate 5-kinase Activity
Biological Process
  • Signal Transduction
  • Blood Coagulation
  • Neural Tube Development
  • Inositol Trisphosphate Metabolic Process
  • Inositol Phosphate Metabolic Process
  • Inositol Phosphorylation
  • Necroptotic Process
Pathways
  • Synthesis of pyrophosphates in the cytosol
  • Synthesis of IP3 and IP4 in the cytosol
  • Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
  • Body mass index ( 26426971)
  • Chronic obstructive pulmonary disease ( 30804561)
  • Endometriosis ( 23472165)
  • Height ( 31562340)
  • Migraine ( 27182965 27322543)
  • Platelet count ( 22139419)
  • Plateletcrit ( 27863252)
  • Thyroid hormone levels ( 23408906)
Interacting Genes 6 interacting genes: COPS8 GPS1 JUN NFKBIA TP53 TRAF2
Entrez ID 3705
HPRD ID 03501
Ensembl ID ENSG00000100605
Uniprot IDs A0A024R6H3 Q13572
PDB IDs 2ODT 2Q7D 2QB5
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025

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